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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5f8310ddb0f6149565a9e2b0c6ae2ede1714ab6dac3e348496239c9513a0b3' 
  AND token = 'cNUvVYh14PupjCepa6lMRanjVHj6bv9mToWVyR5od68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}