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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050338da596ade048cb0db727e5ebc800a4cb4e4e727040775f6a0646a10ef0d' 
  AND token = '19b9kikBkdEB+FrSGeGLAC1jUBgnJm9rYvhrSNPyJZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}