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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a19fdb905b08e556fb7c3ec85ca97550e0303d4d44ff0226bd8770c74ab8566' 
  AND token = 'LF4bUjmBIn4j4vQbJ8CQDRARARLO4IwC8pQ61R6PIVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}