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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6574f84d01c1dad306b2c0920dcc9f92b79e5667cdc54084e80e3156d04f02' 
  AND token = 'lH6So5sgN5/36tETqV1yJIz2y6ps+9BGdauZxwDrkOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}