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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b2fe5c7547d94d515e2dc6d09686fe90d391f61af03d65e712e13324cb3b6f' 
  AND token = 'htWYCC6o5wQwhHcFy7gGlh7K3kBzKBCa6uEFTu790c4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}