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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f078b10748707a1ee8ba289a975bb6a0f8b3eca4fc09c0889fd7779594a3b6cc' 
  AND token = 'k80/VuJ3eC8p3BIK0WNxgtcEb9WSA5bCxpqBl4+lZrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00091

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}