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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdc8f61348d241a0a3ab763819f83df536a094ee3742c8a669d7b201dfab6de8' 
  AND token = 'BkeJZP7hT62O/ICwuMb/xoTWbjB/JfwJ8r/mYtYmpFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}