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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16acef79249c8f8d1ecf044b08b2fe62086d16bc2d2d04faefc57e690442d253' 
  AND token = 'FEktM6xgeho0obG5s9qgtxZuxUWYP+9SmBd+f5Egkng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}