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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722178c97d4d8e71a7bb3b79f4a44a79a24c3f40bf07d3e0ac23a64f3f1d9de4' 
  AND token = 'LATu9FtTvHchLrPo6jPeD5dBT2KZliXXwjubNdh8Il0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}