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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea7e342570ea9948f71d434df384346f8bd2bc4a39c25dbffa89c0d12b4a09a9' 
  AND token = 'PuO2gNoQkxb2QVuQikriQEEcBJu0VlYRD9wG8WHqKtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00085

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}