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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e46f2faf8f7c7fe3e03344583159b9dcbf2a93209541c1e6b4a070390e0e6d2' 
  AND token = 'Myigdza2+aaefgq6EbbwMl8CIPWZxQ36Drs+OORLYwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}