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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457015429af4dff9c83271e1055ca6d2e7c1ddf6511ba1c4762757bf285520cf' 
  AND token = 'HP8CvNXPQhZnPrLgtCUsidswlu+RGaaj5tlS4ol7PXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}