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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be49da5ab84ad29c077c9de17d24c7838feb3709cd69097177f9bdf2285bce51' 
  AND token = '9kBpxbm3YVXRaZf0wfDz7wcB5RpIgQMMF1weok5Y7SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}