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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0d4b9bd01e41b94758fabeccefb593a6a0cd352e46b896bc90ee1f38f857fa' 
  AND token = 'FVbL1BIrGdGQIl1/+MBXqQcpJahlenH6nUO9fulo/Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}