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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5648cc74b2924aa9a8011b494f6ea52bb34d8a5112b340ea18b49cb37d7146ee' 
  AND token = '/sP+ajDM/R13+6lnP37iyN0VS8sAFHQI4SavIURelt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}