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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da3a5d7270dfeb2dde154decc1f086d78512aca72ed823b0f213e51dae764482' 
  AND token = 'H1Om6+TjagHYP6l32iRf+VAJ/CI8AsfJpdqJG7Nm7p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}