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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735daa4d066dcd503713d74002777ba0f6b3de35e7514d7b13e33298cbae55bf' 
  AND token = '4M9bry4QlTnGgAx5PfWGMv/l43Nvi5BAdzK88qDVWpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}