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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd8a5648da4adb3625276fca3e718e1375fe683a55fe702584b73080e02364fe' 
  AND token = 'PiW4GD61tr11GuRUO/CcsixxS20nfv7NIEcx6gPRhH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}