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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3da07668be538a2ec68a9fb0884bf0976e31183ce5ae328e6cc896962d18b772' 
  AND token = 'z22pZQRFYBqN0uHBZyUvyvk5bLnsCvNOPfAC+RXsLFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}