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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62c7b8e9f0a3db06d4d23be86b5b94734aad20cbd84cc4147e89af295116ad1d' 
  AND token = 'ES7MOM6zA3505bo48bj8xrbWWikGXl+D5iQ5CTYmIaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}