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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff606516339baacd5a10edc07c20c793e3db348d10cb66c251d87fab482f2548' 
  AND token = 'Pu/W1IIsfD0VsCbsVjlU++MjaSV58eXkvh0k45Nx2fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}