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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431d57ed9c0d43d840a0e828729f6a129cc68d48eb80e08825f3892093e26e39' 
  AND token = 'JNJaz5SXuGCsxElKgdXeBPeOSY2KNTcCcG0QPekI6Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}