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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a77a2080141088deb7d65b5eb74d1acf790b3aa927faf9549a4a6b518e789cac' 
  AND token = '80hktlwM0u+l1B+oOkM/5JdikvdPib2RrXgJAzhSNcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}