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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db253a86b2da7f49cfd2b2937f621c12439ec9875b85dda6ddebc7f509b1b059' 
  AND token = 'EF0DVkBr1yR5rRe7QsbuegMNGxf7pNBzaUWq7m6SkjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}