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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '188778e3787bcce891c2adf77017c765cb308607543945423fc193e4660cb443' 
  AND token = 'ycB9G+zlUuA+/ORcjJYGQ0NI70geJAmPz3ZOLr23jN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}