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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d511b0722e969d63eb725dd0a5ab28473ca7fb655bff5ef265eb8177a3730d6' 
  AND token = 'jgpDk/9TnZpmwSlx45fJadsJCiGbD8Mym+iFXfGYrC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}