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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6452ca739c886dc9c9e8932bdb78352d0ca43bc02c79e4a51874d07634e43904' 
  AND token = 'gBtRQ45ZXhWq0VRYH3ZPN/hTOOWrhjk0rp12h1laj/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}