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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e86d35a282f581a77504e2f2bda55b87147812a6fc4c542454cfb6ba1fac96e' 
  AND token = 'D4rKMV+A6YgdD7LGLNu9odgxEAXCmHpWaXJ6xpaIHJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}