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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efa81f117c8d7628dbda128d172cbe29bf1ef5fe839a5d596de0897577d33e3' 
  AND token = 'WYmIcFawzEo6inX4AxmpbvP+hnNyaDS+ULKXlbl/yIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}