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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27f2ffc085e5cf133884f2c65aa0f51bcaeb7359f591692634e984d82485a809' 
  AND token = 'vQCbTr8UQuMM+q7E0VzEstt8shqS5zjzYB9iNpKtfHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}