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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e735de16eaa46dc8cdd3b5564c8cdd6b3ea0015dc9973b3933768d444b383362' 
  AND token = '6MnRp5IvwNEjPhzd09ZCvWdFyY6NUIdiJ5on+b3JCYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}