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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a04148e2c32df5fc7dfa03544bd593e5c645e7377e9b628c90566e85799462dc' 
  AND token = 'mp5Y0/X70AiDbIkKfxDXFJaoAQnyxdFUkMtNO1t4tPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}