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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0188ce095698825d4305e98be2ffac8a42547e8a8aa61a021961548e25a2de' 
  AND token = '4H8TP08EvtxRCeQCN7fLLZHhijQUIKOHwc9uqjMUh0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}