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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e59404aa591d6e6a6bd87ecdd56ab86f72fb2a23b53cb06a696d40f93b52b26' 
  AND token = 'p7Jt1DJKV3EL/lBWzX88Br3CR+Mcryokj1pMNjfMOe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}