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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b753954180b2e2b3c9e6e828d2391f21d00037cfaf816ed5e36e631f3e4805d9' 
  AND token = 'P6x5TIEUJzaJQDO6niPz6xBnkS+HH8CfCZGi4Qh51pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}