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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0cfc21104ace24ab76f90ab8cd601a3a937d84f4de992cf79fd77d6d868f271' 
  AND token = '4KpXbapBdRWUeHtPoXHp3s+xHCcT6VckMtaCfYvZgu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}