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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd19ce7e910c14d782eb7b38e048e412594c39f9f67a419fffd786199199a21f' 
  AND token = '175OIoXE0+27dtHI1iiOD+Wi9T0KQlYywlzt7wUCMYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}