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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc9ffb167c18e2993f3321cf001fb28fa02a4dc275c5c81c23bd61b90e0fb1b' 
  AND token = 'F8fTtK+CMMSoqktiS4KlSk+tFlayWr8jYDYc0NyFcok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}