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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22402727da879e263c2fe0c3f6db5ff705e12e61af9db8721a1ad40dde74c676' 
  AND token = 'bLrJfKWbvG0RjDHqQh+BlZy910QaiwZONG1DbT6uzXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}