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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b957a663cea964a61c5308c46044aa22942d80d53941172259abffd31e0df8' 
  AND token = 'I6pfNMt0feVycr/CtWgdO1322axDyFT8VS4mIHQG1y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}