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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6203b1a586064772f14ac897e537919093fc72d345798d0f601ba7bf89f0e09' 
  AND token = '4Dn11fI+69VOo2T2d0WyvG/SAXz91yXTWKJlPeLM3Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}