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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e51fc302f4fb9859beb99d015fbef49b21ee15a6e48bdd85d9451b16470e40' 
  AND token = '09P0TBT8H6WmBNGwPqUG2GmIzGK62fYZfTOu9zcCZ5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}