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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44022b1fa86b2793f40eace28241dbe7de2c96e738ecd5c5f852395c6d287df' 
  AND token = 'Q2MJfVfEvLndP5tUG1DVv8Y/+QxTAx+z29xGRq3SpuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}