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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e291f44f4875409ca481f49b06fda4325fbf6afc768f5568d01aaf9d358eff9e' 
  AND token = '/2nRz8SxGNH36DTt93E5uSnHpvEufAID/PgR3TCvz2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}