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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1ca9b2a38ed26a474e26ec14bab5168962a0f7108d2fc8f7a1fca247316869' 
  AND token = '1Ot8nKK+pfYByy/9CCex9PpqTXcmzbC9Gl6zndG5Gxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}