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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3c6456c57613da008ea8d8634cf5f01758bb18d952df529a3528faec0d71a0' 
  AND token = 'HDK3eCvw8WHcswj0RL/a26T653h/1LvYsZMhCYvXJyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}