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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be05f306e2a52656d2938420683313b92e2fd3cf22e5a8af747fdf7575ca426' 
  AND token = 'iGwC4w+KqLaMDh6hasfSVFqGWJcWzErrI0xniniMV9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}