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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab6fa8ebd15fe8abc1623c57ba83a87b91f9127d9b0dde54b0255049221f1b0' 
  AND token = 'OV95E7h8krDP/6UDt8JiUVGeu9Tyd+RK2WDhNtZuEjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}