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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8608f05345dc9d326ffcaa2f718237be096616c0c47746015055273b64362251' 
  AND token = 'OCdRgll3WVQz/ZAT3BfFi0EP1H31oKBLW0uOf/bKrx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}