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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10a7b5a9e87de179d910666b1667ad298b8713033702695c5c868b798dde4d9' 
  AND token = 'vrqbZ1QmiSM8yCubL6blt7BFv7LuKwSaA3FYyCdfNRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}